Did you check the Item Settings? There's probably one on the map that's set up to spawn drops when played.
Hmmm... taking your advice, I ran through each item settings and took a look but everything looks normal.
I don't think the problem is related to anything I'm doing because there's randomly place items that I'm not using in the editor. For example: when i go into play mode the map there's a randomly placed health regeneration item tucked in the corner in one of the hallways. When I go back to edit mode, that health regeneration isn't there.
Thanks for the assistance.
Are you using the item spawn settings?
Item spawn is set active, probably on starting the map. In item spawn you can determine the frequency of randomly spawned weapons, small items, medium items, large items, and power ups. It's good for map makers that don't want to hassle with dropping down supplies into their map or just filling in the map in general while saving a ton on network space (which anything placed and visible in game eats like I do pizza and candy.)
The node you're looking for is a beg hexagon with a bracketed shield, cross, and gun.